Upregulation of smpd3 via BMP2 stimulation and Runx2
نویسندگان
چکیده
منابع مشابه
Upregulation of smpd3 via BMP2 stimulation and Runx2.
Deletion of smpd3 induces osteogenesis and dentinogenesis imperfecta in mice. smpd3 is highly elevated in the parietal bones of developing mouse calvaria, but not in sutural mesenchymes. Here, we examine the mechanism of smpd3 regulation, which involves BMP2 stimulation of Runx2. smpd3 mRNA expression increased in response to BMP2 treatment and Runx2 transfection in C2C12 cells. The Runx2-respo...
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ژورنال
عنوان ژورنال: BMB Reports
سال: 2009
ISSN: 1976-6696
DOI: 10.5483/bmbrep.2009.42.2.086